我們與國內外眾多合作單位聯合發表的部分文章與摘要(包括 CTC,CTEC,腫瘤細胞與分子生物學,腦神經學,內分泌學,免疫學,血液學,病原微生物學,C-反應蛋白 CRP,免疫脂質體溶破技術應用等



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  • 中文推送(點擊推送題目下載)

    • 58.P. P. Lin (2020) Aneuploid Circulating Tumor-Derived Endothelial Cell (CTEC): A Novel Versatile Player in Tumor Neovascularization and Cancer Metastasis. Cells 9:1539

      關鍵詞:CTEC、腫瘤細胞內皮化、腫瘤微環境、腫瘤新血管生成、腫瘤轉移、hypoxia、EMT、EndoMT
      合作單位:賽特生物
    • 58R. Y. Lei, N. Sun, G. Zhang, C. Liu, Z. Lu, J. Huang, C. Zhang, R. Zang, R. Che, S. Mao, L. Fang, X. Wang, S. Zheng, J. He (2020) Combined detection of aneuploid circulating tumor-derived endothelial cells and circulating tumor cells may improve diagnosis of early stage non-small-cell lung cancer. Clin Transl Med e128

      關鍵詞:肺癌早篩、肺小結節、CTEC、CTC、賽特SE-iFISH
      合作單位:中國國家癌癥中心、中國國家臨床腫瘤醫學研究中心、中國醫學科學院暨北京協和醫學院腫瘤醫院 – 赫捷院士、院長團隊
    • 57. Y. Chen, C. Qi, J. Yuan, D. Liu, Z. Peng, X. Zhang, J. Li, P.P. Lin, Y. Li, L. Shen (2020) Elevated PD-L1 and HER2 expression on aneuploid carcinoma cells in malignant ascites accelerates tumor cell immune evasion in gastrointestinal cancer patients. Cancer Res 80:5381a

      關鍵詞:惡性腹水腫瘤細胞、PD-L1、 HER2、免疫逃逸、胃癌
      合作單位:北京大學腫瘤中心、北京腫瘤醫院、賽特生物
    • 56.? 程洪艷,李一林,王書航,劉穎,王丹丹,林平,昌曉紅 (2020) 應用SE-iFISH同步聯合檢測異倍體CTC與CTEC的重要臨床意義?!杜R床實驗室》(Clinical Laboratory) 14(5):43-48

      關鍵詞:瘤標、異倍體、循環腫瘤血管內皮細胞CTEC、SE-iFISH
      合作單位:北京大學人民醫院婦科腫瘤中心、北京大學腫瘤中心、北京腫瘤醫院、中國國家癌癥中心、中國醫學科學院、北京協和醫學院腫瘤醫院 、賽特生物
    • 55. L. Zhang, X. Zhang, Y. Liu, T. Zhang, Z. Wang, M. Gu, Y. Li, D.D. Wang, W. Li, P.P. Lin (2020)?PD-L1+?aneuploid circulating tumor endothelial cells (CTECs) exhibit?resistance to the checkpoint blockade immunotherapy in advanced NSCLC?patients.?Cancer Lett 469:355-366

      關鍵詞:非小細胞肺癌、PD-L1+ CTC 及 CTEC、免疫治療耐藥
      合作單位:首都醫科大學附屬北京胸科醫院、北京大學腫瘤中心、北京腫瘤醫院、賽特生物
    • 54. Y. Zhao, J. Li, D. Li, Z. Wang, J. Zhao, X. Wu, Q. Sun, P.P. Lin, P. Plum, A. Damanakis, F. Gebauer, M. Zhou, Z. Zhang, H. Schlosser, K-W Jauch, P.J. Nelson, C.J. Bruns (2020) Tumor biology and multidisciplinary strategies of oligometastasis in gastrointestinal cancers.?Semin Cancer Biol 60:334-343

      關鍵詞:腫瘤寡轉移OMD、腫瘤微環境、CTC及CTEC
      合作單位:德國科隆大學、德國慕尼黑大學、上海復旦大學腫瘤中心、上海長海醫院、賽特生物
    • 54R. G. Ma, Y. Jiang, M. Liang, J. Li, J. Wang, X. Mao, J. S. Veeramootoo, T. Xia, X. Liu, S. Wang (2020) Dynamic monitoring of CD45-/CD31+/DAPI+ circulating endothelial cells aneuploid for chromosome 8 during neoadjuvant chemotherapy in locally advanced breast cancer. Ther Adv Med Oncol 12:1-14

      關鍵詞:新輔助化療、乳腺癌、CTEC、CTC、賽特SE-iFISH
      合作單位:江蘇省人民醫院暨南京醫科大學第一附屬醫院乳腺外科、江蘇省乳腺疾病診療中心、江蘇省婦幼保健醫院
    • 53. X. Liu, J. Li, B. L. Cadilha, A. Markota, C. Voigt, Z. Huang, P. P. Lin, D. D. Wang, J. Dai, G. Kranz, A. Krandick, D. Libl, H. Zitzelsberger, I. Zagorski, H. Braselmann, M. Pan, S. Zhu,Y. Huang, S. Niedermeyer, C. A. Reichel, B. Uhl, D. Briukhovetska, J. Suárez, S. Kobold, O. Gires, and H. Wang (2019) Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis (SA Highlights). Science Advances 5, eaav4275

      關鍵詞:乳腺癌轉移、腫瘤動物模型、原代腫瘤細胞培養、EpCAM+ CTCs與DTCs、單細胞測序
      合作單位:上海交大附屬上海第一人民醫院、德國慕尼黑大學、GSK制藥、復旦大學生科院、南京醫科大學、賽特生物等
    • 52. Y. Wang, Y. Liu, L. Zhang, L. Tong, Y. Gao, F. Hu, P. P. Lin, B. Li, T. Zhang (2019)?Vimentin expression in circulating tumor cells (CTCs) associated with liver metastases predicts poor progression-free survival in patients with advanced lung cancer. J Cancer Res Clin Oncol 145:2911-2920

      關鍵詞:SCLC及NSCLC、肺癌定向肝轉移、預后、間質化CTC
      合作單位:首都醫科大學附屬北京胸科醫院、賽特生物
    • 51. Y. Li, X. Zhang, D. Liu, J. Gong, D. Wang, S. Li, Z. Peng, Y. Li, X. Wang, P. Lin, M. Li, and L. Shen (2018) Evolutionary expression of HER2 conferred by chromosome aneuploidy on circulating gastric cancer cells contributes to developing targeted and chemotherapeutic resistance (CCR Highlights). Clin Cancer Res?24:5261-71

      關鍵詞:胃癌、CTC HER2與組織 HER2、CTC與耐藥及不良預后
      合作單位:北京大學腫瘤中心、北京腫瘤醫院、美國奧克拉荷馬大學醫學中心、賽特生物
    • 50. P. Lin, J. Li, D. Wang, O. Gires, H. Wang (2018) EpCAM differentially expressed on circulating and disseminated tumor cells promotes tumor metastasis in breast cancer patients. Cancer Res 78:1059a

      關鍵詞:乳腺癌轉移、EpCAM+ CTCs和DTCs、療效和預后
      合作單位:上海交大附屬上海第一人民醫院、德國慕尼黑大學、賽特生物等
    • 49. J. Zhang, H. Shi, T. Jiang, Z. Liu, P.P. Lin, and N. Chen (2018) Circulating tumor cells with karyotyping as a novel biomarker for diagnosis and treatment of nasopharyngeal carcinoma.?BMC Cancer?18:1133

      關鍵詞:鼻咽癌、CTC檢測、腫瘤分期、化療療效、耐藥
      合作單位:華西醫院腫瘤中心、腫瘤放療科及生物治療國家重點實驗室、賽特生物
    • 48. P. Lin (2018) Aneuploid CTC and CEC.?Diagnostics?8(2):26(1-13)

      關鍵詞:CTC與CTEC、染色體異常、SE-i?FISH、單細胞測序
      合作單位:賽特生物
    • 47. L. Wang, Y. Li, J. Xu, A. Zhang, X. Wang, R. Tang, X. Zhang, H. Yin, M. Liu, D. Wang, P. Lin, L. Shen, J. Dong (2018) Quantified postsurgical small cell size CTCs and EpCAM+ circulating tumor stem cells with cytogenetic abnormalities in hepatocellular carcinoma patients determine cancer relapse.?Cancer Lett?412:99-107

      關鍵詞:肝癌、術后復發、小細胞CTC、EpCAM+ CTC、CTM
      合作單位:清華大學附屬北京清華長庚醫院 – 董家鴻院士、院長團隊、北京大學腫瘤中心、北京腫瘤醫院、解放軍301總醫院、賽特生物
    • 46. X. Li, Y. Zhang, J. Ding, M. Wang, N. Li, H. Yang, K. Wang, D. Wang, P. Lin, M. Li, Z. Zhao, and P. Liu (2017) Clinical significance of detecting CSF-derived tumor cells in breast cancer patients with leptomeningeal metastasis.?Oncotarget?9:2705-14

      關鍵詞:乳腺癌腦轉移、原代腫瘤細胞培養、NGS、指導個體化篩藥
      合作單位:大連醫科大學腫瘤干細胞研究所、大連醫大第二附屬醫院、賽特生物
    • 45. P. Lin, O. Gires, D. Wang, L. Li and H. Wang (2017)?Comprehensive?in situ?co-detection?of aneuploid circulating endothelial and tumor cells.?Sci Rep?7:9789

      關鍵詞:CD31、異倍體循環血管內皮細胞CTEC、腫瘤血管生成、CTC活性
      合作單位:上海市第一人民醫院腫瘤中心、德國慕尼黑大學、賽特生物
    • 44. 由磊,趙燁,闞秀,李一林,王東民,張愛群,王紅霞,劉穎,王丹丹,林平,鄭直?(2017)?同步原位檢測 CTC 多重瘤標蛋白表達與染色體異倍體的意義及應用?!杜R床與實驗病理學雜志》 (J Clin Exp Pathol)?33:297-302

      關鍵詞:液體活檢、CTC、臨床意義
      合作單位:北京協和醫院、中國醫學科學院基礎醫學研究所、北京腫瘤醫院、解放軍301醫院、北京大學第一醫院、賽特生物
    • 44R. W. Wu, Z. Zhang, X. Gao, Z. Shen, Y. Jing, H. Lu, H. Li, X. Yang, X. Cui, Y. Li, Z. Lou, P. Liu, C. Zhang, W. Zhang (2017) Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH) Oncotarget 8:21639

      關鍵詞:結直腸癌、術前與術后CTC、術后復發及預后、SE-iFISH
      合作單位:西安交大附屬陜西漢中3201醫院普外科、上海張江轉化醫學中心、二軍醫大附屬長海醫院結直腸癌外科
    • 43. Y. Li, X. Zhang, D. Liu, J. Gong, D.D. Wang, P.P. Lin, and L. Shen (2017)?Dynamic acquisition of HER2 expression on circulating tumor cells in gastric cancer patients correlates to developing therapeutic resistance.?Cancer Res?77:3795a

      關鍵詞:胃癌、HER2+ CTC、耐藥
      合作單位:北京大學腫瘤中心、北京腫瘤醫院、美國奧克拉荷馬大學醫學中心、賽特生物
    • 42. H. Wang, N. Stoecklein, P. Lin and O. Gires (2017) Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion (Review).?Oncotarget?8:1884-1912

      關鍵詞:CTC與DTC檢測、治療靶標
      合作單位:上海交通大學附屬上海市第一人民醫院腫瘤中心、德國慕尼黑大學、賽特生物
    • 41. Y. Li, X. Zhang, J. Gong, Q. Zhang, J. Gao, Y. Cao, D. D. Wang, P.P. Lin, and L. Shen (2016) Aneuploidy of chromosome 8 in circulating tumor cells correlates with prognosis in patients with advanced gastric cancer.?Chin J Cancer Res?28:579-588

      關鍵詞:晚期胃癌、8號染色體異倍體、CTC、預后
      合作單位:北京大學腫瘤中心、北京腫瘤醫院、賽特生物
    • 40. P. Lin (2016)?NGS analysis of the single CTC or DTC isolated and subtyped by the integrated subtraction enrichment and immunostaining-FISH.?Cancer Res?76:489a

      關鍵詞:EMT、差相富集 、CTC亞類
      合作單位:賽特生物
    • 40R. F. Gao, Y. Cui, H. Jiang, D. Sui, Y. Wang, Z. Jiang, J. Zhao, S. Lin (2016) Circulating tumor cell is a common property of brain glioma and promotes the monitoring system. Oncotarget 7:71330-71340

      關鍵詞:膠質瘤、CTC、療效評估、賽特SE-iFISH
      合作單位:首都醫科大學附屬北京天壇醫院、中國國家神經系統疾病臨床醫學研究中心、北京腦重大疾病研究院、北京腦腫瘤研究重點實驗室、北京清華大學第一附屬醫院
    • 39. P. Lin (2015)?Integrated EpCAM-independent?subtraction enrichment and iFISH strategies?to detect and classify disseminated?and circulating tumors cells.?Clin Transl Med?4(38):1-7

      關鍵詞:SE-iFISH、CTC分類、臨床意義
      合作單位:賽特生物
    • 38. F. Ge, H. Zhang, D. Wang, L. Li and P. Lin (2015)?Enhanced detection and comprehensive?in situ?phenotypic characterization of circulating and disseminated heteroploid epithelial and glioma tumor cells.?Oncotarget?6 (29):?27049-27064

      關鍵詞:CTC 和 DTC 亞型、差相富集 (SE)、原位表型和核型分析 (iFISH)
      合作單位:北京朝陽醫院、復旦大學華山醫院、賽特生物
    • 37. P. Lin, L. Li, and D. Wang (2015) A novel integrated iFISH technology to detect and characterize non-hematopoietic heteroploid CTC subtypes with or without expressing vimentin or other tumor biomarkers.?Cancer Res?75:557

      關鍵詞:iFISH 技術、檢測并分型 CTC
      合作單位:賽特生物
    • 36. J. Jiang, D. Wang,??M. Yang, D. Chen, L. Pang, S. Guo, J. Cai, J.P. Wery,?L. Li, H. Li,and P. Lin (2015)?Comprehensive characterization of chemotherapeutic efficacy on metastases in the established gastric neuroendocrine cancer patient derived xenograft model.?Oncotarget?6(17):15639-15651

      關鍵詞:CTC 亞型、轉移性 PDX、耐藥、表型和核型分析 (iFISH)
      合作單位:北京大學天然藥物與仿生藥物國家重點實驗室、中美冠科生物技術有限公司、賽特生物
    • 35. Y.Li, X. Zhang, S. Ge, J. Gao, J. Gong, M. Lu, Q. Zhang, Y. Cao, D. Wang, P. Lin, L. Shen (2014) Clinical Significance of Phenotyping and Karyotyping of Circulating Tumor Cells in Patients with Advanced Gastric Cancer.?Oncotarget? 5(16):6594-6602

      關鍵詞:胃癌、CTC、核型分析、耐藥監測
      合作單位:北京大學腫瘤中心、北京腫瘤醫院、賽特生物
    • 34. R. Ran, L. Li, M. Wang, S. Wang, Z. Zheng, and P. Lin (2013) Determination of EGFR mutation in single cells microdissected from enriched lung tumor cells in peripheral blood.?Anal. Bioanal. Chem.?405(23):7377-7382

      關鍵詞:肺癌、CTC、單細胞測序、EGFR 突變
      合作單位:北京協和醫院、中國科學院基礎醫學研究所、賽特生物
    • 33. J. Jiang, D.D. Wang, M. Yang, D. Chen, S. Guo, J. Cai, L. Li, J-P. Wery, P. Lin, and H. Li (2013) Metastatic PDX modeling displays correlation between CTC and metastatic potential, both inhibited by chemotherapy.?Mol. Cancer Ther.?12:157

      關鍵詞:PDX 模型、CTC 、轉移潛能
      合作單位:中美冠科生物技術有限公司、賽特生物
    • 32. Q. Chen, F. Ge, W. Cui, F. Wang, Z. Yang, Y. Guo, L. Li, R. Bremner, and P. Lin (2013) Lung Cancer Circulating Tumor Cells Isolated by the EpCAM-Independent Enrichment Strategy Correlate with Cytokeratin 19-Derived CYFRA21-1 and Pathological Staging.?Clin. Chim. Acta 419:57-61

      關鍵詞:肺癌、CTC、病理分期、CYFRA21-1
      合作單位:北京協和醫院、世紀壇醫院、圣約瑟夫醫院、賽特生物
    • 31. X. Zhou, L. Li, H. Hao, S. Wang, Z. Guo, M. Wang, L. Zhang, W. Zhong, R. Ran, X. Zhang, L. Xu, and P. Lin (2010) Circulating tumor cells as a prognostic and predictive indicator in advanced lung cancer patients.?Oncol. Progress?8(5):484-490

      關鍵詞:肺癌、CTC、療效
      合作單位:北京協和醫院、首都醫科大學附屬北京胸科醫院、賽特生物
    • 30. C. Wu, H. Hao, L. Li, X. Zhou, Z. Guo, L. Zhang, X. Zhang, W. Zhong, H. Guo, R. Bremner, and P. Lin (2009) Preliminary investigation of the clinical significance of detecting circulating tumor cells enriched from lung cancer patients.?J. Thorac.?Oncol.?4:30-36

      關鍵詞:循環腫瘤細胞 (CTC) 、肺癌、CT、化療療效評估、復發
      合作單位:北京協和醫院、北京微生物與流行病研究所、賽特生物
    • 29. P. Lin, C. Lavoie, T. Fischer, H. Huang, and M. Farquhar (2009) Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells.?
      Mol. Neurodegener.?4:1-16

      關鍵詞:G-蛋白、調節性細胞外泌
    • 28. L. Li, X. Zhou, H. Hao, M. Wang, Z. Guo, S. Wang, X. Xing, G. Harvie, E. Vuong, W. Shi, M. Tang, J. Rao, T. Reid, R. Bremner, P. Lin, J. Xu (2008) Detection of circulating tumor cells in newly diagnosed or relapsed lung cancer patients and the significance of CTC enumeration in patient staging.?Cancer Res.?68:3691

      關鍵詞:非小細胞肺癌、CTC 計數、臨床分期、影像學
      合作單位:加州大學洛杉磯分校、加州大學圣地亞哥分校、圣約瑟夫醫院、賽特生物
    • 27. D. Wang, Y, Liu, Y. Liu, C. Wang, H. Bao, H. Hao, S. Wang, Y. Zhang, H. Yu, X. Xing, G. Harvie, E. Vuong, J. Rao, T. Reid, P. Lin, J. Xu (2008) Enrichment and detection of circulating tumor cells in breast cancer patients.?Cancer Res.?68:3692

      關鍵詞:乳腺癌、分期與療效、CTC 計數
      合作單位:北京大學第一醫院、加州大學圣地亞哥分校、賽特生物
    • 26. H. Guo, H. Hao, Z. Li, Y. Zhu, J. Sun, F. Ge, S. Wang, X. Xing, G. Harvie, E. Vuong, J. Rao, R. Bremner, T. Reid, P. Lin, J. Xu (2008) Preliminary investigation of lung cancer CTC distribution in patient body circulation.?Cancer Res.?68:3694

      關鍵詞:肺靜脈、橈動脈和外周血 CTC 、顯著性差異
      合作單位:北京協和醫院、加州大學圣地亞哥分校、賽特生物
    • 25. Y, Chen, H. Bao, C. Zhou, X. Xing, G. Harvie, E. Vuong, J. Rao, T. Reid, H. Qiu, Y. Xiao, H. Wu, M. Mei, C. Lu, P. Lin and J. Xu (2008) Detection of circulating tumor cell in patients with colorectal cancer and its potential implication.?Cancer Res.?68:3696

      關鍵詞:結直腸癌、CTC、腫瘤侵襲性
      合作單位:北京協和醫院、加州大學圣地亞哥分校、加州大學洛杉磯分校、賽特生物
    • 24. X. Zhou, L. Li, M. Wang, L. Zhang, P. Lin and J. Xu (2008) Circulating tumor cells (CTC) as a prognostic and predictive factor in lung cancer patients.?J Clin Oncol?26(15):22201

      關鍵詞:肺癌、CTC、預后
      合作單位:北京協和醫院、賽特生物
    • 23. C. Ren, P. He, J. Zhang, Z. Zheng, Y. Xu, L. Zhou, H. Qiao, C. Wang, P. Zhao, W. Shi, M. Tang, P. Lin, and J. Xu (2007) Detecting circulating tumor cells in peripheral blood of pancreatic cancer patients using negative selection strategy. Cancer Res.?67:5445

      關鍵詞:差相富集、CTC、胰腺癌
      合作單位:中國國家癌癥中心、中國國家臨床腫瘤醫學研究中心、中國醫學科學院腫瘤醫院、賽特生物
    • 22. W. Shi, T. Reid, M. Tang, G. Harvie, H. Tao, G. Tao, P. Lin, and J. Xu (2007) Detection of circulating cancer cells from lung cancer patient blood samples and correlation with anti-cancer therapy.?Cancer Res.?67:5444

      關鍵詞:肺癌、CTC、化療
      合作單位:北京協和醫院、加州大學圣地亞哥分校、賽特生物
    • 21. H. Yu, P. Lin, Y. Xu, Y. Zhou, Q. Sun, and J. Xu (2007) Breast cancer and circulating tumor cells (Review).?Chn. J. Med. Lab.?Tech.?8(3):215-218

      關鍵詞:乳腺癌、循環腫瘤細胞
      合作單位:北京協和醫院、賽特生物
    • 20. Y. Chen, P. Lin, S. Qiu, XX. Peng, K. Loi, MG Farquhar and JY. Zhang (2007) Autoantibodies to Ca2+?binding protein Calnuc is a potential marker in colon cancer detection.?Int. J. Oncol.?30(5):1137-44

    • 19. P. Lin, F. Li, Y. Zhang, H. Huang, G. Tong, M. Farquhar and H. Xu (2007) Calnuc binds to Alzheimer’s beta-amyloid precursor protein and affects its biogenesis.?J. Neurochem.?100:1505-1514

    • 18. Y. Chen, P. Lin, K. Looi, R. Megliorino, and J. Zhang (2005) Autoantibodies to calcium binding protein Calnuc might be a potential marker in colon cancer detection.?Cancer Res.?65:561

    • 17. P. Lin, C. Ren, X. Zhao, L. Li, Y. Qiao , G. Harve, H. Tao, E. Vuong, G. Tao, M, Huang, L. Wu, and J. Xu (2005) Role of detecting circulating tumor cell in clinical cancer diagnosis and therapy.?Chn. J. Lab. Tech.?1 (1):1-6

      關鍵詞:循環腫瘤細胞檢測、臨床腫瘤診斷和治療
      合作單位:中國國家癌癥中心、中國國家臨床腫瘤醫學研究中心、中國醫學科學院腫瘤醫院、北京協和醫院、賽特生物
    • 16. Y-W. Zhang, W-J Luo, H. Wang, P. Lin, K.S. Vetrivel, F. Liao, F. Li, P.C. Wong, M.G. Farquhar, G. Thinakaran, and H. Xu (2005) Nicastrin is critical for stability and trafficking but not association of other presenilin/γ-secretases components.?J.?Biol. Chem.?280:17020-17026

    • 15. C. Lavoie, T. Meerloo, P. Lin , and M.G. Farquhar (2002) Calnuc, an EF-Hand Ca2+-binding protein, is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT-20 cells.?Mol. Endocrinol.?16:2462-2474

    • 14. T.S.Weiss, C.E. Chamberlain, T. Takeda, P. Lin, K.M. Hahn, and M.G. Farquhar (2001) Galphai3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer (FRET) of green fluorescent protein fusion proteins.?Proc. Natl. Acad. Sci. USA. 98:14961-14966

    • 13. P. Lin, T. Fischer, T. Weiss, and M.G. Farquhar (2000) Calnuc, an EF-hand Ca2+?binding protein, specifically interacts with the C-terminal alpha5-helix region of Galphai3.?Proc. Natl. Acad. Sci. USA. 97:674-679

    • 12. P. Lin, C. Lavoie, T. Fischer and M.G. Farquhar (2000) Calnuc regulates ACTH secretion in AtT-20 cells.?Mol. Biol. Cell?11:50

    • 11. P. Lin, Y. Yao, R. Hofmeister, R.Y. Tsien and M.G. Farquhar (1999) Overexpression of CALNUC (nucleobindin) increases agonist and thapsigargin relesable Ca2+?storage in the Golgi.?J. Cell Biol.?145:279-289

    • 10. P. Lin, T. Fischer, T. Weiss, and M.G. Farquhar (1999) Calnuc, an EF-hand Ca2+?binding protein, specifically interacts with the C-terminal region of Galphai3.?Mol. Biol. Cell?10:418

    • 9.P. Lin, H. Le-Niculescu, R. Hofmeister, J.M. McCaffery, M. Jin, H. Hennemann, T. McQuistan, L. De Vries, and M.G. Farquhar (1998) The mammalian Ca2+?binding protein, nucleobindin (CALNUC), is a Golgi resident protein.?J. Cell Biol. 141:1515-1527

    • 8.P. Lin, Y. Yao, R. Hofmeister, R.Y. Tsien and M.G. Farquhar (1998) Overexpression of CALNUC increases agonist and thapsigargin relesable Ca2+?storage in the Golgi.?Mol. Biol. Cell?9:99

    • 7. H. Le-Niculescu, P. Lin, M. Jin, H. Hennemann, D. Heinegard, T. McQuistan, J. M. McCaffery, N. Watson, L. De Vries, and M.G. Farquhar (1997) Characterization of a Golgi-associated EF-hand/ Ca2+?binding protein that interacts with heterotrimeric Galphai protein subunits.?Mol. Biol. Cell?8:338

    • 6. Y-P. Li, G. Curley, M. Lopez, M Chavez, R. Glew, A. Aragon, H. Kumar, and O.G. Baca (1996) Protein-tyrosine phosphatase activity of?Coxiella Burnetii?that inhibits human neutrophils.?Acta Virologica?40:263-272

    • 5. P. Lin, C. Mold, and T.W. DuClos (1995) Characterization of the C-reactive protein (CRP) receptor on the human monocytic cell line THP-1 (704).?Immunol.?Today?16(7):305-62

    • 4. O.G. Baca, Y-P. Li, and H. Kumar? (1994) Survival of the Q fever agent?Coxiella Burnetii?in the phagolysosome.?Trends in?Microbiol.?2(12):476-480

    • 3. Y-P. Li, C. Mold, and T.W. DuClos (1994) Sublytic Complement Attack Exposes C-Reactive Protein Biding Sites on Cell Membranes.?J. Immunol.?152:2995-3005

    • 2. T. Nakagaki, P. Lin, and W. Kisiel (1992) Activation of human factor VII by the prothrombin activator from the venom of?Oxyuranus Scutellatus(taipan snake).?Thrombosis Res.?65:105-116

    • 1. P. Lin, Q.S. Lin, and S.Q. Nie (1992) Primary study of application of liposome immunolysis assay on drug monitoring.?Prog.?Clin. Biochem.p515-516. Editors: K. Miyai, T. Kanno, and E. Ishikawa. Excerpta Medica Publishing.

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